Karl Fischer & Potentiometric Titration Application Library
Analysis of Water Content in Gasoline and Fuel Oil
Low water content determination in gasoline and fuel oil with an oil evaporator
Total Acid and Amino Acid Determination in Beverages Like Sake
Easy and accurate determination of total acidity and total amino acid content in beverages like Sake
Determining Acidity in Fruit Beverages
Accurate and Automatic Determination of Acidity in Fruit Beverages Like Orange Juice
Acid and Salt Determination in Colored Samples Like Plum Sauce
Accurate and automatic Determination of Acid and Salt with Colored Samples Like Plum Sauce
Salt Determination in Difficult Samples Like Soy Sauce
Salt Determination Without the use of toxic Potassium Chromate
Acid and Salt Determination in Colored Samples Like Ketchup
Continuous Analysis for Acid and Salt in colored samples like ketchup
ASTM D974 Acid Number in Refrigerant Oils
Automatic measurement of acid number in refrigerant oils with an error-free photometric probe
Peroxide Measurement in Edible Oils
Simple, reliable and easy measurement of peroxide in fats and cooking oils with a potentiometric titrator
Standardization of hydrochloric acid titrant | Autotitrator COM-A19
The measurement method of alkaline substance by neutralization titration using a hydrochloric acid standard solution is widely used in the titration analysis. Factors are indicated on the commercially available standard solution for volumetric analysis. The factor determination is required when the standard solutions are prepared in the laboratory.
Drugs and Medicines – KF Volumetry, Back-Titration, Japanese Pharmacopoeia – Suitability test | Karl Fischer titrator AQV-300/MOIVO-A19
Water contents of drugs and medicines could be determined by Karl Fischer volumetric titrator. In volumetric titration, the titrant have a factor which means the ability to react with how many milligrams of water per 1 mL of titrant. Factor is pre-determined before sample measurement and water content of sample is calculated from consumed titrant volume within sample measurement.
There are two methods in KF volumetric titration, forward-titration and back-titration. Forward-titration is used in general. However, some of the sample should be measured by back-titration method according to Pharmacopeias.
In this report, the suitability test of Japanese Pharmacopoeia Eighteenth Edition was performed for dextromethorphan hydrobromide monohydrate, also introduced in Application Data No. 11, with back-titration method. Please refer to Application Data No. 11 for the factor determination of titrants procedure and the repeatability of measurement results for dextromethorphan hydrobromide monohydrate.
There are two methods in KF volumetric titration, forward-titration and back-titration. Forward-titration is used in general. However, some of the sample should be measured by back-titration method according to Pharmacopeias.
In this report, the suitability test of Japanese Pharmacopoeia Eighteenth Edition was performed for dextromethorphan hydrobromide monohydrate, also introduced in Application Data No. 11, with back-titration method. Please refer to Application Data No. 11 for the factor determination of titrants procedure and the repeatability of measurement results for dextromethorphan hydrobromide monohydrate.
