Karl Fischer & Potentiometric Titration Application Library
Moisture Determination in Pharmaceuticals by Karl Fischer Back-Titration (Japanese Pharmacopoeia Method)
Karl Fischer moisture determination in pharmaceuticals using back-titration methods. Ensure compliance with Japanese Pharmacopoeia and accurate QC results.
Moisture Determination in Pharmaceuticals by Karl Fischer Titration
Karl Fischer moisture determination in pharmaceuticals following Japanese Pharmacopoeia methods. Ensure accurate, compliant quality control results.
Sugars – KF Volumetry, granulated sugar Factor standardization with water standard | Karl Fischer titrator AQV-300/MOIVO-A19
This application introduces an example for the water determination in granulated sugar. Due to the low water content of this sample, a relatively large amount of sample must be added, but the solubility in methanol as titration solvent is not sufficient. Sugars have tendency to dissolve in formamide. Therefore a mixed solvent of formamide and methanol was chosen as the titration solvent. To make it easier to dissolve the sample, the titration cell was heated to 45 °C using an outer chamber for flowing warm water.
Since the water content of the granulated sugar is often a few hundred ppm, the titrant with low factor value, as 1 mg/mL was used. When pure water is used as the standard material of factor standardization for low factor titrant, the amount of pure water added should be as small as 10 to 20 mg, which makes accurate addition and weighing difficult. Therefore, water standard material which is the solution containing 1 % of water sealed in glass ampoule is used for the factor standardization.
Moisture Determination in Sugars (Glucose, Fructose, Sucrose) Using Karl Fischer Titration
Accurate moisture determination in sugars using Karl Fischer titration. Analyze glucose, fructose, and sucrose powders with reliable, reproducible results.
Moisture Determination in Ketones and Aldehydes by Karl Fischer Titration (Avoiding False High Results)
Avoid false moisture results in ketones and aldehydes during Karl Fischer titration. Understand side reactions and improve analytical accuracy.
Moisture Determination in Pharmaceutical Powders by Karl Fischer Titration
👉 Moisture determination in pharmaceutical powders using Karl Fischer titration. Accurate analysis of excipients and amino acid compounds.
Moisture Determination in Pharmaceutical Excipients by Karl Fischer Titration
Moisture determination in pharmaceutical excipients and surfactants using Karl Fischer titration. Accurate analysis for reliable quality control.
Moisture Determination in Pharmaceuticals by Karl Fischer Back-Titration
Moisture determination in pharmaceuticals using Karl Fischer back-titration. Ideal for complex or reactive samples requiring accurate results.
Moisture Determination in Pharmaceutical Solvents by Karl Fischer Titration (Direct Injection)
Moisture determination in pharmaceutical solvents such as propylene glycol and glycerin using Karl Fischer titration. Ideal for direct injection analysis.
