Karl Fischer & Potentiometric Titration Application Library
Determination of sodium acetate with perchloric acid titration | Autotitrator
Sodium acetate is widely used in chemical and medical industry (E.g. Buffer, Antifreezing agent, Alkalizing supplements, Dye chemical, Hydragogue). Determination method of sodium acetate is described on Japanese Pharmacopoeia and Japanese Industrial Standard (JIS K8371). Both methods employ perchloric acid titration method, dissolve the sample in glacial acetic acid and titrate with perchloric acid – acetic acid standard solution. Endpoint is detected by potentiometric titration with glass / reference electrodes.
CH₃COONa ＋ HClO₄ → CH₃COOH ＋ NaClO₄
CH₃COONa ＋ HClO₄ → CH₃COOH ＋ NaClO₄
