CAPCELL CORE Core-Shell HPLC Columns
High Efficiency Separation at Moderate System Pressure
CAPCELL CORE columns utilize advanced core-shell (superficially porous) particle technology to deliver high separation efficiency while maintaining moderate backpressure. The 2.7 µm core-shell design reduces band broadening and improves mass transfer, resulting in sharper peaks and increased resolution compared to conventional fully porous particles of similar size.
CORE columns are ideal for laboratories seeking faster analysis and improved performance without requiring ultra-high-pressure LC systems.
Why Choose Core-Shell Technology?
Core-shell particles consist of a solid core surrounded by a thin porous layer. This structure:
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Improves chromatographic efficiency
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Reduces diffusion path length
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Delivers high theoretical plate counts
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Maintains manageable system pressure
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Enables shorter run times without sacrificing resolution
This makes CAPCELL CORE particularly suitable for high-throughput LC and LC-MS workflows.
Available CORE Selectivities
The CAPCELL CORE series includes multiple stationary phase options to address a wide range of analytical challenges:
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CORE C18 – General-purpose reversed-phase separations
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CORE ADME – Enhanced retention of highly polar metabolites
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CORE AQ (C27) – Stable operation in highly aqueous mobile phases
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CORE PFP – Alternative selectivity for isomeric and aromatic compounds
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CORE PC (HILIC mode) – Enhanced hydrophilicity for polar analytes
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CORE MP – Mid-pore design for higher molecular weight compounds
Ideal Applications
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High-speed reversed-phase separations
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LC-MS bioanalysis
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Polar compound retention challenges
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Isomer separations
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High-efficiency analysis on conventional HPLC systems
For assistance selecting the appropriate CORE phase for your application, contact JM Science technical support to sales@jmscience.com or Tel: 716-774-8706