Analytical Applications and Methods

Accurate control of free acid and total acid is essential for consistent phosphate coating performance. Learn how automated titration improves repeatability and process control.

Non-aqueous titration is widely used for the assay of pharmaceutical drug substances that are not suitable for aqueous analysis. Potentiometric titration provides accurate and reliable results for these challenging compounds.

The mixed solution of nitric acid and phosphoric acid works as strong acid, and also has the strong oxidizability and solvency. It is used as the surface treatment solution for metals, glass products, and semiconductors.

This report introduces an example of the fractional and successive determination for nitric acid and phosphoric acid by neutralization titration with sodium hydroxide standard solution. When nitric acid and phosphoric acid are titrated by neutralization titration using a glass electrode for pH measurement, two inflection points appear on the titration curve. The first inflection point appears as the total amount of nitric acid and phosphoric acid (reaction formula (1) and (2)). Sodium dihydrogen phosphate, which is the product of reaction equation (2), subsequently reacts with sodium hydroxide and shows an inflection point in the second stage (reaction equation (3)). Therefore, it is possible to obtain the phosphoric acid concentration from the second inflection point, and nitric acid concentration could be obtained with subtracting titration volume at the second inflection point from the first inflection point.

Boric acid is a critical buffer in nickel plating baths. Learn how automated potentiometric titration with mannitol improves accuracy, repeatability, and process control.

Accurate sodium sulfate determination in formulated products using potentiometric titration. Reliable QC method using lead ion-selective electrode.