If your method specifies a Brownlee Aqueous C18 column, you’re not alone.
Many pharmaceutical, environmental, and QC methods developed over the past 20–30 years still reference this exact column configuration.
We supply the original Brownlee column for method compliance and validation requirements—but we also support customers who are looking for:
- Improved performance
- Better availability
- Lower operating cost
- Easier long-term supply
👉 Not sure if you need the original? Contact us—we can help you evaluate equivalent columns with minimal method impact.
⚠️ Important Note (this drives behavior)
Most customers purchasing this column fall into one of two categories:
-
Regulated labs that must match the original validated method
-
Labs looking for a replacement due to cost, availability, or performance
If you are in category #2, we strongly recommend reviewing modern alternatives before purchasing.
🔄 Modern Alternatives (THIS IS WHERE YOU MAKE MONEY)
We offer high-performance replacements for aqueous C18 applications, including:
➤ CAPCELL PAK Aqueous-Compatible Phases
- Excellent retention under 100% aqueous conditions
- Superior peak shape for polar compounds
- Highly stable silica technology
- Widely used in pharma and bioanalysis
👉 In many cases, these columns:
- Match or exceed Brownlee performance
- Reduce method variability
- Lower overall cost per analysis
Contact us for a recommended equivalent based on your method.
📊 When Should You Use the Original Brownlee?
You should consider this OEM column if:
- Your method explicitly specifies Brownlee Aqueous C18
- You are working under GMP / GLP / regulatory conditions
- You are performing method validation or transfer studies
- Revalidation is not practical or cost-effective
📦 Product Specifications
- Column Type: Aqueous-compatible C18
- Dimensions: 250 × 4.6 mm
- Particle Size: 5 µm
- Application: Polar compounds under aqueous mobile phases
- Format: Analytical column
💬 Call to Action (must be strong)
Not sure if you need the original Brownlee column?
We can:
- Recommend a direct replacement
- Help you transition to a modern column
- Improve separation of difficult polar compounds
👉 Request a quote or technical recommendation today
Contact Info: sales@jmscience.com; Tel: 716-774-8706
