Karl Fischer Overview Page | JM Science
H1: Karl Fischer Moisture Analysis
Karl Fischer titration is a trusted method for precise moisture analysis across industries. JM Science offers a complete range of Coulometric KF titrators for ultra-trace moisture detection and Volumetric KF titrators for moderate-to-high moisture samples. Learn more about each type below to choose the best solution for your laboratory.
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H2: What is Karl Fischer Titration?
Karl Fischer (KF) titration is a chemical method for accurately determining water content in samples. It can detect trace amounts of water with coulometric titration or moderate to high moisture with volumetric titration. KF titration is widely used in pharmaceuticals, chemicals, food, and polymers for quality control and regulatory compliance.
H2: Coulometric vs Volumetric KF Titrators
Choosing the right KF titrator depends on your sample type and moisture range. The table below highlights the key differences:
| Feature | Coulometric KF | Volumetric KF |
|---|---|---|
| Measurement Range | Trace levels: 10 µg – 10 mg H₂O | Higher moisture: 0.01 – 500 mg H₂O |
| Titrant | Electrochemically generated iodine (no pre-made titrant) | Pre-prepared titrant (manual or automated burette) |
| Best For | Very low moisture samples | Moderate to high moisture samples |
| Speed | Slower for large samples | Faster for larger samples |
| Sample Types | Liquids, solids, gases (trace moisture) | Liquids, solids, pastes (higher moisture) |
| Automation | Fully automated for small samples | Automated burette systems for moderate/high volume |
| Accuracy | ±1 µg H₂O or better | ±0.1 – 1 mg H₂O depending on model |
| Applications | Pharmaceuticals, oils, polymers, chemicals with trace water | Food & beverages, chemicals, pharmaceuticals, polymers with moderate/high moisture |
| Compliance | ASTM E203, ISO 760, JIS K0068 | ASTM E203, ISO 760, JIS K0068 |
| Maintenance | Low, minimal reagents | Low, replace titrant as needed |
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For detailed information on each type, visit our Coulometric KF Titrators or Volumetric KF Titrators pages.
H2: Applications
Karl Fischer titration is widely used for:
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Pharmaceuticals: raw materials, tablets, capsules
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Chemicals: solvents, acids, hygroscopic powders
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Food & Beverages: sugar, oils, dairy, beverages
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Polymers & Resins: moisture monitoring in pellets and films
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Environmental labs: moisture in soil, gases, and liquids
For industry-specific guidance, see our application notes.
H2: Support & Resources
H2: Request a Quote or Demo
Ready to streamline moisture analysis in your lab?
Request a Quote →
or call (716) 774-8706 to speak with a technical specialist or send email to sales@jmscience.com