Capcell Pak C18 ACR | HPLC Column | Particle Size 3μm

Osaka SodaSKU: JM-811

Inner Diameter (mm): 4.0 mm
Length (mm): 10 mm Guard Cartridge Column
Sale price$210.00 USD


Capcell Pak C18 ACR (ACR stands for Acidic Resistance) has the highest level of acid resistance in the lineup of columns offered by Osaka Soda. This HPLC column has high selectivity for planar structure compounds and polymeric separation characteristics. It is suitable for continuous use in the low pH range and analysis of structural isomers. 

This packing material realizes not only basic resistance but also outstanding acidic resistance generated by further improvements to the polymer coating technology used for CAPCELL PAK. This column can be used under strongly acidic conditions (pH 1 to 2) and low organic contents.


  • Top acidic resistance

Proved by a unique severe acid resistance test (pH 1). Optimum for peptide mapping where TFA and formic acid are frequently used



HPLC Conditions

Mobile Phase: (A) 2 vol% TFA in H2O (pH = 1)
(B) 2 vol% TFA in acetonitrile
B solution: 65% (20 min) → 0% (60 min) → 90% (5 min) → 65% (5 min)
Temperature: 60°C
Flow Rate: 1.0mL/min
Detection: UV 254nm
Samples: Uracil and amylbenzene
  • Minimal residual silanol groups

Polymer coating technology minimizes hydrogen bonding, which is a parameter reflecting the influence of residual silanol groups

【Fig. 3】

  • Free from tailing

Sharp peak shapes achieved by strictly controlled polymer coating

  • Full range of column sizes

A complete lineup from microcolumns of 0.3 mm i.d. to LC-MS fast columns 20 mm long and semi-preparative columns

Pore size
Particle size
Specific surface area
(m 2/g)
C% Density
(µmol/m 2)
Functional group Acceptable pH USP
8 5 300 17 2.6 Octadecyl group 1~10 L1
8 3 300 17 2.6 Octadecyl group 1~10 L1


Application Data 

 Capcell Pak C18 ACR Application Library

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